--- title: "Targeted Peptide Support" url: https://spokemed.com/clinical-services/targeted-peptide-support/ date: 2026-02-26 modified: 2026-09-17 lang: en author: "support@totoseo.com" description: "Schedule an Exploration Call Targeted Peptide Support at SPOKEmed If you're dealing with stubborn weight, low energy, hormonal shifts, or slow recovery, peptide therapy may offer targeted support where general..." word_count: 2278 --- # Targeted Peptide Support [Schedule an Exploration Call](https://spokemed.com/book-now/) ## Targeted Peptide Support at SPOKEmed If you're dealing with stubborn weight, low energy, hormonal shifts, or slow recovery, peptide therapy may offer targeted support where general solutions have fallen short. SPOKEmed provides clinically guided peptide therapy for weight loss, metabolic health, tissue repair, and healthy aging, each protocol prescribed after a full clinical review of your history, labs, and goals. All medications are sourced from a licensed U.S. compounding pharmacy and shipped directly to patients. Prescription services are available to eligible patients in states where licensure permits and in accordance with applicable laws. [Schedule Your Targeted Peptide Support](https://spokemed.com/book-now/) ## What Are Peptides and How Does This Work? Peptides are short chains of amino acids that occur naturally in the body and function as biological messengers. They regulate hormone signaling, immune response, tissue repair, metabolism, and cellular communication. Peptide therapy uses specific bioactive peptides to support these pathways with precision, addressing where your body needs help rather than applying a generalized approach. At SPOKEmed, peptide therapy is overseen by Michelle Middleton, PA-C, who brings over a decade of clinical experience in weight management, hormonal health, and metabolic medicine. Therapies are selected based on your health history, symptoms, lab results, and long-term goals, not trends. ### GHK-Cu: Skin, Hair & Tissue Repair As we age, GHK-Cu levels in the body naturally decline, and with them, the speed of tissue repair, skin resilience, and inflammation control. GHK-Cu is a naturally occurring copper-binding peptide found in human plasma that supports collagen production, wound healing, and healthy cell turnover. SPOKEmed uses GHK-Cu therapy to restore these functions in patients experiencing aging-related tissue decline. #### What It May Support - Skin firmness, elasticity, and tone - Collagen and elastin production - Reduction in fine lines and wrinkles - Wound healing and tissue repair - Hair growth and follicle health - Reduction in oxidative stress and inflammation #### Administration Protocol | Dose | 1.5 mg daily | | ---- | ------------ | | Schedule | 5 days on / 2 days off | | Duration | 6-12 weeks, followed by an equal rest period | | Noticeable results | Typically after 4-6 weeks | ### NAD+ - Cellular Energy & Brain Health NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme essential for cellular energy production, mitochondrial function, and DNA repair. Levels decline with age, chronic stress, inflammation, and illness, contributing to fatigue, brain fog, and metabolic slowdown. Restoring NAD+ levels may boost energy, support mitochondrial efficiency, and improve both metabolic and cognitive health. #### What It May Support - Energy, stamina, and endurance - Brain health and cognitive function - DNA repair and cellular resilience - Reduced inflammation - Cardiovascular and neurological health - Recovery, detoxification, and mood regulation #### Administration Protocol | Dose | 50-100 mg | | ---- | --------- | | Frequency | 2-3 times weekly | | Administration | Subcutaneous injection | ### BPC-157: Tissue Healing & Gut Health BPC-157 is a peptide derived from a compound found in gastric juice, well established for its role in tissue healing and inflammation reduction. It supports recovery from musculoskeletal injuries and gastrointestinal conditions and can be administered systemically or near a specific injury site. SPOKEmed also offers gut microbiome testing to assess intestinal health before and during therapy, providing a measurable baseline for gut-related protocols. #### What It May Support - Tendon, ligament, and muscle repair - Joint and bone healing - Pain and inflammation reduction - Collagen synthesis - Gut lining and intestinal health - Neuroprotective effects #### Administration Protocol | Dose | 250-500 mcg daily | | ---- | ----------------- | | Administration | Subcutaneous injection or near injury site | | Duration | 4-6 weeks, followed by a break | ### Glutathione: Detoxification & Antioxidant Support Glutathione is the body's primary antioxidant, critical for detoxification, immune defense, and cellular protection. Levels decline with aging, stress, toxin exposure, and illness. Injectable glutathione delivers more reliable absorption than oral forms and works synergistically with NAD+ for combined cellular and metabolic support. #### What It May Support - Liver detoxification - Reduced oxidative stress - Immune function - Skin clarity and tone #### Administration Protocol | Dose | 200 mg (1 mL) | | ---- | ------------- | | Frequency | 1-2 times weekly | | Administration | Intramuscular or subcutaneous | ## Metabolic Therapies: Fat Loss and Energy The following therapies support fat metabolism, energy production, and metabolic efficiency. At SPOKEmed, these are prescribed as part of a structured weight management plan, not in isolation. ## GLP-1 and Incretin-Based Medications for Medical Weight Loss GLP-1 medications, known as glucagon-like peptide-1 receptor agonists, are among the most clinically studied weight loss medications available. Drugs in this class, including semaglutide (known by the brand name Ozempic) and tirzepatide (Mounjaro), work by regulating blood sugar levels, controlling appetite, promoting satiety, and slowing gastric emptying. At SPOKEmed, these medications are prescribed as part of a comprehensive medical weight loss plan, not as standalone solutions. ### Tirzepatide - Dual GLP-1 / GIP Agonist Tirzepatide activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual mechanism improves insulin sensitivity, reduces appetite, controls blood sugar levels, and enhances metabolic efficiency. It supports significant weight loss while preserving lean mass when paired with proper nutrition and strength training. - Administration: Subcutaneous injection, once weekly, gradually titrated based on tolerance ## Emerging Therapies Under Clinical Review The following therapies are offered selectively at SPOKEmed. Both are investigational, and long-term safety data is still evolving. Neither has received full FDA approval for weight management. Michelle Middleton, PA-C, reviews each patient's history and clinical profile before recommending either protocol. These therapies are not appropriate for all patients. ## The SPOKEmed Treatment Model At SPOKEmed, every peptide or metabolic therapy is paired with a structured care plan. No medication is prescribed in isolation. Protocols include: - Nutrition optimization with adequate protein and micronutrients - Strength training and movement guidance - Hormone evaluation and optimization when appropriate - Follow-up appointments every three to four weeks with dose adjustments as needed - Direct access to Michelle Middleton, PA-C, by phone and text between visits The goal is sustainable weight loss, muscle preservation, and long-term metabolic health, not rapid results that reverse when therapy ends. Expert Care, Wherever You Are ## Who We Serve SPOKEmed provides personalized care through secure telemedicine, making expert guidance accessible from wherever you call home. New prescription-based medical services are currently available for patients located in Florida. For those outside Florida, personalized health coaching and wellness support remain available nationwide. Telehealth coaching & wellness ### Care for women, nationwide Non-prescription services are available to patients across the country. From Jupiter to Jacksonville and beyond, expert care comes to you wherever you are. Proudly serving [Jupiter](https://spokemed.com/service-areas/health-and-wellness-coach-in-jupiter/)[Palm Beach County](https://spokemed.com/service-areas/health-wellness-coach-palm-beach-county/)[Palm Beach Gardens](https://spokemed.com/service-areas/health-wellness-coach-palm-beach-gardens/)[West Palm Beach](https://spokemed.com/service-areas/hormone-replacement-therapy-in-west-palm-beach-fl/)[patients nationwide via telehealth](https://spokemed.com/book-now/) Prescription services are available where permitted by applicable laws and licensure. [Book a Consultation](https://spokemed.com/book-now/) By appointment only. In-person visits available in Florida; telehealth available nationwide. ## Real Patients. Real Results. Feedback highlighting the personalized approach and medical guidance patients receive as they work toward restoring balance from the inside out, with SPOKEmed. ![Google](https://cdn.trustindex.io/assets/platform/Google/logo.svg) Excellent![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)5.037 reviews 5.0![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg) Excellent37 reviews [Write a review](https://admin.trustindex.io/api/googleWriteReview?place-id=ChIJN5Vn_DmOwY4REP26eg_W55Y) Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Katrina Eggertsson profile picture](https://lh3.googleusercontent.com/a/ACg8ocK4onm_j8dBS8I19w9J0KjU87kG7thB0CJNAoHwwNHjAO0eeg=w40-h40-c-rp-mo-br100) Katrina Eggertsson 21 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is amazing! Super knowledgeable and helpful! If you’re looking for help to a healthy lifestyle she is the one you want help from. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Greta Lambert profile picture](https://lh3.googleusercontent.com/a-/ALV-UjVu5E4xW8J4Fo-Ej2d0pdp_tSPhBU87qMAGdmxBxQvWUlJfw8Gf=w40-h40-c-rp-mo-br100) Greta Lambert 37 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Dr. Michelle Middleton has been such a blessing in my life. She has helped me learn good habits not only for meals, but for living a happy, life of joy. I am so grateful for her guidance and tips. She is amazing! Her guidance has helped me emotionally and physically. She has helped me lose weight and to love myself again! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Michelle Chavers profile picture](https://lh3.googleusercontent.com/a-/ALV-UjUoT3jUSV3UsNhIqIcBL1vpGNngtB_EsEfwNO-4p-nkk32Ypigi=w40-h40-c-rp-mo-ba12-br100) Michelle Chavers 37 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle helped me with my crazy hormones when others told me I just needed to ride the perimenopause rollercoaster. That answer wasn’t good enough for me. I wanted to feel better. When I found Michelle she got me on the correct HRT and supplements I needed to feel better. It’s made a big difference in my mood and daily routine. I would highly recommend her as a woman trying to understand our complex body in midlife! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Celeste Mikes profile picture](https://lh3.googleusercontent.com/a/ACg8ocIIWiJyiqKM-L2izgfLvaL_-QzUK2ApJt7zYmjsIJhTw-evnA=w40-h40-c-rp-mo-br100) Celeste Mikes 75 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. SPOKEmed is a very knowledgeable with weight loss. They take the time to speak with you directly and walk you through the process. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![danielle cruz profile picture](https://lh3.googleusercontent.com/a/ACg8ocIHngxkakx0pqI4aU2mTq-tKJRsnMB0MintnwAwyIYwwUJgNA=w40-h40-c-rp-mo-br100) danielle cruz 177 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is a wealth of knowledge and has done so much to help me dig into root causes - both physiologically as well as mentally. I appreciate her comprehensive approach to wellness, her patience and her ongoing coaching! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Lisa B profile picture](https://lh3.googleusercontent.com/a/ACg8ocK-avI7EjVEl84cdA3oUvuyVNCb48PaPZPhSkn5Sx3_5FyfnA=w40-h40-c-rp-mo-br100) Lisa B 191 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is lovely to work with. She takes adequate time to listen and has useful and practical solutions. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Judith Rosbrook profile picture](https://lh3.googleusercontent.com/a/ACg8ocKNHtp9r_gSjNJgzNzO9K28W_976iMCfsFjtO0bRYVsqYlm9jY9=w40-h40-c-rp-mo-br100) Judith Rosbrook 193 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. I’ve been counseling with Michelle for almost a year. She has your best interest at heart! She’s very knowledgeable and recommends what’s best for your health! Thank you for everything Michelle!!! JR Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![ilissa siegel profile picture](https://lh3.googleusercontent.com/a/ACg8ocK5dWnwzpOjxekqARA3AZqXr8HkzCn0ushVtNNZ8kXv7Z_4gQ=w40-h40-c-rp-mo-br100) ilissa siegel 198 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. SpokeMED/Michelle is very knowledgeable and always accessible/helpful. She looks at your health and wellbeing holistically and has helped me feel like the best version of myself. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Ali Loomis profile picture](https://lh3.googleusercontent.com/a-/ALV-UjVadlfLKD_3KVNbCtIl6sbCccUAv0EdxIm5-gniAbSliZzjnDqy8g=w40-h40-c-rp-mo-br100) Ali Loomis 200 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Working with Michelle has been wonderful! She is clear, informative, and makes sure all of my questions have been answered. She is personable, supportive, and easy to talk to. I highly recommend her! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Nancy Hortman profile picture](https://lh3.googleusercontent.com/a-/ALV-UjVdQHAtZIW_IRHH8YHLorZWvBEJUewwbL5sMS5s69GNV1HiKeOZ=w40-h40-c-rp-mo-br100) Nancy Hortman 200 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle, is absolutely wonderful! She is beyond helpful and wise and cares woud recommend !! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Joni House profile picture](https://lh3.googleusercontent.com/a/ACg8ocLVDKzhUwtJeA4QQWUobtUvYH_mHOrB6t6D-TtX8PlPvvgScQ=w40-h40-c-rp-mo-br100) Joni House 206 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Working with SPOKEmed has truly transformed my health and focus. The guidance, accountability, and encouragement is helping me build better habits and gain clarity. I am thankful for the positive impact they have had on my life. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Rhina Mendoza profile picture](https://lh3.googleusercontent.com/a/ACg8ocIarboXuU40fVYqx2cT-foizPKwFVBnxwuJr80pZghSnhqAVg=w40-h40-c-rp-mo-br100) Rhina Mendoza 207 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. I have nothing but excellent reviews with this service, very friendly and knowledgeable people, love it , thanks Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Rolanda Montenegro profile picture](https://lh3.googleusercontent.com/a/ACg8ocIr8zAMax6UK_9_3b5ICSetsF_r4l8oKlQ293HceqvQia_o4tA=w40-h40-c-rp-mo-br100) Rolanda Montenegro 208 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Love working with Michelle! She answers all my questions and shows extreme understanding and care with her clients. I felt very good knowing she was there to walk me through this process. Highly recommend her services! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Katie Norman profile picture](https://lh3.googleusercontent.com/a/ACg8ocJdsPhHVM7qTrBi8EIQSY9MZPPALAePOdwgvA3Bw6cb_qOg3g=w40-h40-c-rp-mo-br100) Katie Norman 212 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is wonderful! Michelle is so supportive, responsive and encouraging. She truly listens to your concerns and provides sound solutions and guidance. She truly cares for her patients. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Pawfessional Mobile Vet profile picture](https://lh3.googleusercontent.com/a-/ALV-UjVJdSyTonlQEBgN4fMHeSJjTsikGO-1XGNzCPSaUqV_Ww5IORU=w40-h40-c-rp-mo-br100) Pawfessional Mobile Vet 217 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is wonderful to work with and provides exceptional advice! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Tim Ellenburg profile picture](https://lh3.googleusercontent.com/a-/ALV-UjWZ1BD9d59ygmx60wXUmxZnL9WQrHJaVs_OtxakTQ1C3Td7dQ=w40-h40-c-rp-mo-br100) Tim Ellenburg 221 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Close attention to detail, thorough coverage of information Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![L.S.C profile picture](https://lh3.googleusercontent.com/a/ACg8ocKp9Vig2UnPV8px5eAKrm1RolcQe4hFadf72jpGJj0T37IMbQ=w40-h40-c-rp-mo-br100) L.S.C 227 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Kas profile picture](https://lh3.googleusercontent.com/a/ACg8ocIz5Ny2uMee0QlzplHhxKdiNHFkQ1UBbnvVrc-PFLVvoOv8rQ=w40-h40-c-rp-mo-br100) Kas 235 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is very knowledagble, kind and is always willing to help if I have a question about something. She makes sure she gives enough info on the glp1 shot for her clients to be successful. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Katie Sefton profile picture](https://lh3.googleusercontent.com/a/ACg8ocIOsLFz-uv4vXVxQOhawxVr9en_Rs8juxBgsm0YSJ_9pauSAQ=w40-h40-c-rp-mo-br100) Katie Sefton 241 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. I’ve been working with Michelle for several months and have lost over 50 lbs at a healthy pace. It is easy to arrange appointments and she is flexible with the need to reschedule. She listens well and offers on point advice without judgement. She seems to love helping people on their journey to better health and is very knowledgeable about current best practices. I highly recommend SPOKEmed. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Jenna profile picture](https://lh3.googleusercontent.com/a/ACg8ocL9vB8PKIWsqv5jlcuNcQbQxo8cMKNuNM5UPT7qGX6rEp8AoQ=w40-h40-c-rp-mo-br100) Jenna 501 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. I can’t say enough positive things about working with Michelle! She has been instrumental in my weight loss journey with GLP-1 and Lipomino injections. She is so supportive, incredibly knowledgeable, and always willing to answer my questions. She truly listens and takes the time to understand my needs and goals. Her availability and accommodating nature have made this process smooth and reassuring. I’m so grateful to have her guidance and expertise! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Sumner Lane profile picture](https://lh3.googleusercontent.com/a-/ALV-UjUWqXjqQJt7jnI0tQ324-62YkMRJntAl1fmbLeteB9X38huMNxn=w40-h40-c-rp-mo-br100) Sumner Lane 504 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is knowledgeable, attentive, and takes the time to explain her treatments clearly, making me feel comfortable and informed. I appreciate how easy it is to communicate with her and efficiency of visits. She truly cares for her clients and their health. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Natalie Crain profile picture](https://lh3.googleusercontent.com/a-/ALV-UjX3GI7AjdRZjEf-f5E35LWgigCcEM8bLny1wOGThna7Qo-X_Zp8Eg=w40-h40-c-rp-mo-br100) Natalie Crain 526 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Very engaging, cares about my progress, extremely knowledgeable and supportive of my journey. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Franklin E Corvaia II profile picture](https://lh3.googleusercontent.com/a/ACg8ocJ8ncw6_59-H0rltZT7Fjmtm7yZ-PU6eir6zWufvASnhBKqN-Q=w40-h40-c-rp-mo-br100) Franklin E Corvaia II 549 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Thank you for your health education and expertise on my weight loss journey. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Michele Sabin profile picture](https://lh3.googleusercontent.com/a-/ALV-UjW4b1hLM9J5tkc-GCYtyPp-wtrcnX9jrd8VaeT5qxGFc9d1Np88pw=w40-h40-c-rp-mo-br100) Michele Sabin 550 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. I have really enjoyed working with Michelle Middleton. She is helping me reach my optimal health goals with proven solutions, great advice and expertise. She’s incredible!! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Colleen McKenzie profile picture](https://lh3.googleusercontent.com/a/ACg8ocJSM2uLoX6T3JERFlmIiH6hLirwilLKjpkvQ7kClsPQwEqfvg=w40-h40-c-rp-mo-br100) Colleen McKenzie 624 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. I’ve lost 11 lbs in less than 3 weeks. A genuine caring person. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Melissa Staelens profile picture](https://lh3.googleusercontent.com/a-/ALV-UjVJALUJ2Ik5OLOXVcoXlEiPEMVEKM1HCQKmIgbaA9q7McW60IM4yg=w40-h40-c-rp-mo-br100) Melissa Staelens 638 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle has provided amazing support as I continue in my journey towards better health. She helps provide tools that make getting healthy easier and attainable! So thankful to have found her! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![MM profile picture](https://lh3.googleusercontent.com/a/ACg8ocIGumFMquwXvOnTlle3w27YRqMW3of5PTgxM3SE6CYbFuOfoQ=w40-h40-c-rp-mo-br100) MM 641 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is just amazing! From our very first conversation she listens to what I am looking for, addresses all my concerns and she patiently answers all my questions. She is also an incredible positive force and a fantastic cheerleader as I continue my journey of growing and learning in regards to my health and happiness! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Arden Ellis profile picture](https://lh3.googleusercontent.com/a-/ALV-UjVTGTIpa9WI83B_e9PuWRmZj5AcQGtkN-cgfiN9Hf_QeDfu1QL5=w40-h40-c-rp-mo-br100) Arden Ellis 645 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is just the best. She helps you look at the WHOLE picture not just one aspect of your health. It's so important to take the time to really understand each patient's specific needs, issues our health goals, and Michelle does this like no one I've ever met. I am so grateful for her expertise and commitment to her patients. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Susan Martin profile picture](https://lh3.googleusercontent.com/a/ACg8ocJrDtGeQrWhzCW3L6pky-s0H7EkFTgwWgLBQLG6OvGyX2wqIA=w40-h40-c-rp-mo-br100) Susan Martin 664 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. When one comes across something or someone of exceptional quality, you want to share it. That is what I would like to do w/ Michele Middleton. Michelle reached out to me with a suggestion of treatment and course of action to repair and restore my destructive behavior and thinking the program she believes in is good very good but her skills in repairing and Restoration are exceptional. Never judgmental always viewing it from let’s redirect it. Bottom line always with love the heart of hers is full and giving all the time I find her a gift from above Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Jennifer Riggs profile picture](https://lh3.googleusercontent.com/a/ACg8ocLgcAVzsxC25OqyUaqGjyPTtGCj28QiFs6eiuO0PeaWd-ryYg=w40-h40-c-rp-mo-br100) Jennifer Riggs 666 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. ![](https://lh3.googleusercontent.com/grass-cs/ACvplmNV9J2ZPiLfAlqgmkYprxKbjNV6MPMZ-s7rotD9R79OwuOe15897LrpkOtVA2eSHOonN8aegdMvV3OmUj36aFZHEgHw_ljWCkypy5Iq7vmgW01lSmnt7ZlEeV1M_2y3DMwn5OhMaQ=k-no)+0Michelle- has been there for my health journey every step of the way. She turns a negative into a positive and at times when I wanted to give in, she was right there for me. She is a big part of my success and continues to support me. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Shannon Perry profile picture](https://lh3.googleusercontent.com/a-/ALV-UjWQ6GLRraLR5k8_WhyBSMddes0A5IXGWonMVxs-ZVdR7VW6X2Fy=w40-h40-c-rp-mo-br100) Shannon Perry 667 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle Middleton, P.A. Is one of the most caring & careful health care professionals I’ve ever encountered! The world needs more Michelle’s! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Enid Roper profile picture](https://lh3.googleusercontent.com/a/ACg8ocIEufsAEKjF77xDpa7L7GnqA2nrvl6T1V5rka_FEEOoCuRr4Q=w40-h40-c-rp-mo-br100) Enid Roper 690 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is wonderful. Knowledgable, professional, and really explains things well. Made the process so easy. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Troy M profile picture](https://lh3.googleusercontent.com/a-/ALV-UjX2R7kdniVS7rTuhuEVuNfjhc2lvUcVlb3xA1hFtxjhlXZnu_c=w40-h40-c-rp-mo-ba12-br100) Troy M 696 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle has been absolutely amazing. She is thorough, professional and takes the time to not just listen to my health concerns, but addresses them in a way that is easy to understand. Very pleased with the journey so far and am looking forward to continue my health journey with her. Crystal F. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Karla McCoy profile picture](https://lh3.googleusercontent.com/a/ACg8ocKx4gMNm4-nrXyZVWWwJT4WyBsgVqoGXd3eI37CUtQ_natUKA=w40-h40-c-rp-mo-br100) Karla McCoy 696 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle has been an essential part of my health journey. She is knowledgeable, always available to answer my questions when needed, and always ready to help and encourage me. I highly recommend her to anyone ready to start their health journey. Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Marty McCravy profile picture](https://lh3.googleusercontent.com/a-/ALV-UjWmkIraR5igtLl9-73vGDyhthcLHxwe0gQPoU-jAC89wPUTkcc=w40-h40-c-rp-mo-br100) Marty McCravy 696 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is a fantastic coach. She is so knowledgeable and helpful. I highly recommend Michelle for your weight loss journey Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Charlin Burdick profile picture](https://lh3.googleusercontent.com/a-/ALV-UjUuV5ICf0poI_XH20s-rL8JT-3-tvaN-m3yEq7pMHUuyHQugvA=w40-h40-c-rp-mo-br100) Charlin Burdick 703 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. Michelle is absolutely amazing!!! She is beyond professional and listens to her patients needs and concerns. She has been my guide in this journey answering questions, addressing concerns and helping me bridge the gap in achieving my health & nutrition goals. She is incredibly intelligent & respectful and so easy to connect with as well! Do yourself a favor and schedule a consultation and see for yourself. You’ll thank me later!! Posted on Google ![Google](https://cdn.trustindex.io/assets/platform/Google/icon.svg) ![Gerry Gerrard profile picture](https://lh3.googleusercontent.com/a-/ALV-UjXzunBEBe868bD1UuTOYDB_zUZzJXfVGfuj6PbzoDCynegnw4E=w40-h40-c-rp-mo-ba12-br100) Gerry Gerrard 743 days ago ![Google star 1](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 2](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 3](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 4](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)![Google star 5](https://cdn.trustindex.io/assets/platform/Google/star/f.svg)Trustindex verifies that the original source of the review is Google. My friend lost 8 pounds in 2 weeks through this program of a healthy lifestyle and healthy eating. She stopped drinking alcohol (which is miraculous) and eats regularly but healthy all day long and feels GREAT! shes in it to win it and can't wait to get to her ideal weight! Verified by Trustindex Trustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. [Read more](https://www.trustindex.io/?a=sys&c=verified-badge&url=/the-trustindex-verified-badge/) ## Frequently Asked Questions About Targeted Peptide Support ### Can I buy peptides online without seeing a provider first? Peptides sold online without clinical oversight vary significantly in purity, concentration, and suitability for human therapeutic use. At SPOKEmed, all peptide and GLP-1 therapies need a prescription, issued only after a consultation with Michelle Middleton, PA-C. Every therapy is selected based on your medical history, current health status, and treatment goals, not purchased on request. ### How do GLP-1 medications work, and how does tirzepatide compare to semaglutide? GLP-1 medications, glucagon-like peptide-1 receptor agonists, work by mimicking a hormone the body naturally produces to help patients manage their blood sugar, suppress appetite, and promote feelings of fullness and satiety. Semaglutide and tirzepatide both act on the GLP-1 pathway, but tirzepatide also activates the GIP receptor, giving it a dual mechanism of action that may produce stronger metabolic results. SPOKEmed currently offers tirzepatide as its primary GLP-1-based therapy. ### What does the scientific literature say about peptides for weight loss? Research on weight loss peptides, including GLP-1 receptor agonists and targeted peptide fragments, is well established and continues to expand. Clinical studies consistently show meaningful reductions in body weight, improved metabolic markers, and measurable reductions in body fat, particularly in patients with high body fat levels or metabolic dysfunction. SPOKEmed's protocols are built around this evidence and applied within the clinical context of each patient. ### Are SPOKEmed's peptides naturally derived or lab-synthesized? Most therapeutic peptides are clinically tested, synthesized versions of amino acid sequences that occur naturally in the body or in biological compounds. Peptides are low molecular weight molecules, small chains that are well tolerated and targeted in their action. For example, BPC-157 is derived from a protein found in gastric juice, and GHK-Cu is a natural peptide found in human plasma, both replicated for clinical use. SPOKEmed sources the highest-quality peptides from an FDA-certified compounding pharmacy to ensure consistent purity and potency. ### Who is not a candidate for GLP-1 medications? Patients with a personal or family history of medullary thyroid carcinoma, or a diagnosis of multiple endocrine neoplasia syndrome type 2, are not candidates for GLP-1 receptor agonist therapy. Patients with certain endocrine conditions, uncontrolled hypertension, or other relevant contraindications are evaluated individually before any prescription is issued. A full medical history review is required prior to prescribing any GLP-1 or incretin-based medication at SPOKEmed. ### Do GLP-1 medications help with conditions beyond weight management? GLP-1 medications were originally developed for the treatment of type 2 diabetes. Tirzepatide, for example, is FDA-approved for both diabetes management and obesity treatment. Research has also documented significant implications for obesity-related conditions including fatty liver disease, hypertension, and cardiovascular risk. At SPOKEmed, these medications are prescribed for medical weight loss and metabolic health, not exclusively for patients with a type 2 diabetes diagnosis. ### Is berberine a real alternative to GLP-1 therapy? Berberine is a natural compound with modest clinical evidence for improving insulin sensitivity and glucose metabolism, and it is sometimes described informally as a "natural GLP-1" option. While berberine may offer mild metabolic support, its mechanism of action and potency differ substantially from pharmaceutical GLP-1 receptor agonists. Patients comparing options should discuss their specific health profile with Michelle Middleton, PA-C, to determine what level of clinical intervention is appropriate. ### What weight loss results can I realistically expect? Average weight loss varies based on the specific therapy, dosage, starting body mass index, adherence, and how consistently the protocol is followed alongside diet and physical activity changes. SPOKEmed does not pursue rapid weight loss as a primary goal. The focus is on sustainable weight loss that preserves lean muscle and improves long-term metabolic health. Individual weight loss goals and realistic timelines are discussed in detail at your initial consultation. ### What is a growth hormone secretagogue and does SPOKEmed offer one? A growth hormone secretagogue is a compound that triggers growth hormone releasing signals in the pituitary gland, stimulating natural growth hormone secretion. AOD-9604, offered at SPOKEmed, is a peptide fragment of human growth hormone engineered specifically to burn fat through lipolysis without activating broader growth hormone secretion or affecting blood sugar levels. This makes it a targeted metabolic tool rather than a systemic growth hormone intervention. ### How is dosage for injectable peptides determined? Dosage for injectable peptides at SPOKEmed is determined based on your medical history, treatment goals, body weight, and the specific therapy being prescribed. Most peptides are injected subcutaneously, beneath the skin using a small insulin-style syringe, and patients receive clear self-administration instructions before their first dose. Dosages are reviewed and adjusted at follow-up appointments, which occur every three to four weeks. ### Do the peptides require any preparation before use? Some peptides are supplied as lyophilized (freeze-dried) powder that requires reconstitution before injecting. SPOKEmed provides patients with straightforward instructions for easy mixing and preparation, and all steps are explained by Michelle Middleton, PA-C, or her team before you begin. Injectable medications supplied as ready-to-use solutions require no reconstitution. ### How does liraglutide compare to the GLP-1 options at SPOKEmed? Liraglutide is an earlier GLP-1 receptor agonist, marketed as Victoza for type 2 diabetes and Saxenda for obesity or overweight, that requires daily injection. SPOKEmed's current protocols center on tirzepatide and investigational incretin therapies, which offer once-weekly dosing, broader metabolic mechanisms, and, in clinical studies, greater average weight loss outcomes than liraglutide. Patients are matched to the most appropriate therapy based on their individual clinical profile. ### Can peptide therapy help patients with overweight or obesity who are not diabetic? Yes. SPOKEmed's metabolic therapies, including GLP-1 medications and targeted peptides like AOD-9604, are appropriate for patients managing overweight or obesity regardless of a type 2 diabetes diagnosis. Prescription-based weight loss treatment through SPOKEmed is currently available for qualified new patients located in Florida following a clinical evaluation. Personalized health coaching services are available nationwide. Obesity management at SPOKEmed includes structured guidance on diet and physical activity alongside medical therapy. ## Schedule a Consultation with SPOKEmed A consultation with Michelle Middleton, PA-C, is the first step. She will review your health history, labs, and goals and explain exactly which therapies are appropriate, what to expect, and what the full cost of your plan would be. There is no obligation. ### Availability Monday 8:00 AM - 6:00 PM Tuesday 8:00 AM - 6:00 PM Wednesday 8:00 AM - 6:00 PM Thursday 8:00 AM - 6:00 PM Friday 8:00 AM - 6:00 PM All therapies require a clinical consultation prior to prescribing. Investigational therapies carry additional review requirements. Nothing on this page constitutes medical advice. [Book Your Consultation ](https://spokemed.com/book-now/) ## Learn More About Our Services [ View All Our Services ](https://spokemed.com/clinical-services/) ### Weight Loss & Weight Management Hormonal changes can affect metabolism and weight; address both for optimal results [Learn More](https://spokemed.com/clinical-services/medical-weight-loss-management/) ### Health Coaching Get the accountability coach and support you need for lasting change [Learn More](https://spokemed.com/clinical-services/health-coaching/) ### HRT Hormone Replacement Therapy Feel better [Learn More](https://spokemed.com/clinical-services/gut-health-microbiome-testing/) ### Gut Health & Microbiome Testing Identify gut imbalances and get personalized solutions for your overall health and wellness. [Learn More](https://spokemed.com/clinical-services/gut-health-microbiome-testing/) Let's be friends [ @SPOKEmed Instagram ](https://www.instagram.com/spokemed) @ [ @SPOKEmed Facebook ](https://www.facebook.com/profile.php?id=61564399674406) ![SPOKEmed Instagram post sharing menopause facts for women in midlife](https://spokemed.com/wp-content/uploads/2026/02/menopause-facts.jpg) ![SPOKEmed Instagram post on low libido and hormone imbalance in women](https://spokemed.com/wp-content/uploads/2026/02/low-libido.jpg) ![SPOKEmed Instagram: why midlife muscle health matters for women's metabolism](https://spokemed.com/wp-content/uploads/2026/02/midlife-muscles-matter.jpg) ![SPOKEmed Instagram post: the role of cortisol in weight gain and hormonal health](https://spokemed.com/wp-content/uploads/2026/02/lets-talk-about-cortisol.jpg) **REFERRAL PROGRAM** --- Join Our Referral Program and Get Rewarded for Spreading Wellness [Learn About Our Referral Program](https://spokemed.com/referral/) **BEFORE & AFTER** --- Explore Real Before-and-After Success Stories [See Success Stories](https://spokemed.com/results/)