Targeted Peptide Support

Targeted Peptide Support at SPOKEmed

If you're dealing with stubborn weight, low energy, hormonal shifts, or slow recovery, peptide therapy may offer targeted support where general solutions have fallen short. SPOKEmed provides clinically guided peptide therapy for weight loss, metabolic health, tissue repair, and healthy aging, each protocol prescribed after a full clinical review of your history, labs, and goals.

All medications are sourced from a licensed U.S. compounding pharmacy and shipped directly to patients. Prescription services are available to eligible patients in states where licensure permits and in accordance with applicable laws.

What Are Peptides and How Does This Work?

Peptides are short chains of amino acids that occur naturally in the body and function as biological messengers. They regulate hormone signaling, immune response, tissue repair, metabolism, and cellular communication. Peptide therapy uses specific bioactive peptides to support these pathways with precision, addressing where your body needs help rather than applying a generalized approach.

At SPOKEmed, peptide therapy is overseen by Michelle Middleton, PA-C, who brings over a decade of clinical experience in weight management, hormonal health, and metabolic medicine. Therapies are selected based on your health history, symptoms, lab results, and long-term goals, not trends.

GHK-Cu: Skin, Hair & Tissue Repair

As we age, GHK-Cu levels in the body naturally decline, and with them, the speed of tissue repair, skin resilience, and inflammation control. GHK-Cu is a naturally occurring copper-binding peptide found in human plasma that supports collagen production, wound healing, and healthy cell turnover. SPOKEmed uses GHK-Cu therapy to restore these functions in patients experiencing aging-related tissue decline.

What It May Support

  • Skin firmness, elasticity, and tone
  • Collagen and elastin production
  • Reduction in fine lines and wrinkles
  • Wound healing and tissue repair
  • Hair growth and follicle health
  • Reduction in oxidative stress and inflammation

Administration Protocol

Dose 1.5 mg daily
Schedule 5 days on / 2 days off
Duration 6-12 weeks, followed by an equal rest period
Noticeable results Typically after 4–6 weeks

NAD+ — Cellular Energy & Brain Health

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme essential for cellular energy production, mitochondrial function, and DNA repair. Levels decline with age, chronic stress, inflammation, and illness, contributing to fatigue, brain fog, and metabolic slowdown. Restoring NAD+ levels may boost energy, support mitochondrial efficiency, and improve both metabolic and cognitive health.

What It May Support

  • Energy, stamina, and endurance
  • Brain health and cognitive function
  • DNA repair and cellular resilience
  • Reduced inflammation
  • Cardiovascular and neurological health
  • Recovery, detoxification, and mood regulation

Administration Protocol

Dose 50–100 mg
Frequency 2–3 times weekly
Administration Subcutaneous injection

BPC-157: Tissue Healing & Gut Health

BPC-157 is a peptide derived from a compound found in gastric juice, well established for its role in tissue healing and inflammation reduction. It supports recovery from musculoskeletal injuries and gastrointestinal conditions and can be administered systemically or near a specific injury site. SPOKEmed also offers gut microbiome testing to assess intestinal health before and during therapy, providing a measurable baseline for gut-related protocols.

What It May Support

  • Tendon, ligament, and muscle repair
  • Joint and bone healing
  • Pain and inflammation reduction
  • Collagen synthesis
  • Gut lining and intestinal health
  • Neuroprotective effects

Administration Protocol

Dose 250-500 mcg daily
Administration Subcutaneous injection or near injury site
Duration 4–6 weeks, followed by a break

Glutathione: Detoxification & Antioxidant Support

Glutathione is the body's primary antioxidant, critical for detoxification, immune defense, and cellular protection. Levels decline with aging, stress, toxin exposure, and illness. Injectable glutathione delivers more reliable absorption than oral forms and works synergistically with NAD+ for combined cellular and metabolic support.

What It May Support

  • Liver detoxification
  • Reduced oxidative stress
  • Immune function
  • Skin clarity and tone

Administration Protocol

Dose 200 mg (1 mL)
Frequency 1–2 times weekly
Administration Intramuscular or subcutaneous

Metabolic Therapies: Fat Loss and Energy

The following therapies support fat metabolism, energy production, and metabolic efficiency. At SPOKEmed, these are prescribed as part of a structured weight management plan, not in isolation.

GLP-1 and Incretin-Based Medications for Medical Weight Loss

GLP-1 medications, known as glucagon-like peptide-1 receptor agonists, are among the most clinically studied weight loss medications available.

Drugs in this class, including semaglutide (known by the brand name Ozempic) and tirzepatide (Mounjaro), work by regulating blood sugar levels, controlling appetite, promoting satiety, and slowing gastric emptying.

At SPOKEmed, these medications are prescribed as part of a comprehensive medical weight loss plan, not as standalone solutions.

Tirzepatide - Dual GLP-1 / GIP Agonist

Tirzepatide activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual mechanism improves insulin sensitivity, reduces appetite, controls blood sugar levels, and enhances metabolic efficiency. It supports significant weight loss while preserving lean mass when paired with proper nutrition and strength training.

  • Administration: Subcutaneous injection, once weekly, gradually titrated based on tolerance

Emerging Therapies Under Clinical Review

The following therapies are offered selectively at SPOKEmed. Both are investigational, and long-term safety data is still evolving. Neither has received full FDA approval for weight management. Michelle Middleton, PA-C, reviews each patient's history and clinical profile before recommending either protocol. These therapies are not appropriate for all patients.

The SPOKEmed Treatment Model

At SPOKEmed, every peptide or metabolic therapy is paired with a structured care plan. No medication is prescribed in isolation. Protocols include:

  • Nutrition optimization with adequate protein and micronutrients
  • Strength training and movement guidance
  • Hormone evaluation and optimization when appropriate
  • Follow-up appointments every three to four weeks with dose adjustments as needed
  • Direct access to Michelle Middleton, PA-C, by phone and text between visits

The goal is sustainable weight loss, muscle preservation, and long-term metabolic health, not rapid results that reverse when therapy ends.

Expert Care, Wherever You Are

Who We Serve

SPOKEmed provides personalized care through secure telemedicine, making expert guidance accessible from wherever you call home. New prescription-based medical services are currently available for patients located in Florida. For those outside Florida, personalized health coaching and wellness support remain available nationwide.

Telehealth coaching & wellness

Care for women, nationwide

Non-prescription services are available to patients across the country. From Jupiter to Jacksonville and beyond, expert care comes to you wherever you are.

Proudly serving

Prescription services are available where permitted by applicable laws and licensure.

By appointment only. In-person visits available in Florida; telehealth available nationwide.

Real Patients. Real Results.

Feedback highlighting the personalized approach and medical guidance patients receive
as they work toward restoring balance from the inside out, with SPOKEmed.

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Excellent37 reviews
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Katrina Eggertsson profile picture
Katrina Eggertsson
14 days ago
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Michelle is amazing! Super knowledgeable and helpful! If you’re looking for help to a healthy lifestyle she is the one you want help from.
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Greta Lambert profile picture
Greta Lambert
30 days ago
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Dr. Michelle Middleton has been such a blessing in my life. She has helped me learn good habits not only for meals, but for living a happy, life of joy. I am so grateful for her guidance and tips. She is amazing! Her guidance has helped me emotionally and physically. She has helped me lose weight and to love myself again!
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Michelle Chavers
30 days ago
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Michelle helped me with my crazy hormones when others told me I just needed to ride the perimenopause rollercoaster. That answer wasn’t good enough for me. I wanted to feel better. When I found Michelle she got me on the correct HRT and supplements I needed to feel better. It’s made a big difference in my mood and daily routine. I would highly recommend her as a woman trying to understand our complex body in midlife!
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Celeste Mikes
68 days ago
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SPOKEmed is a very knowledgeable with weight loss. They take the time to speak with you directly and walk you through the process.
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danielle cruz
170 days ago
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Michelle is a wealth of knowledge and has done so much to help me dig into root causes - both physiologically as well as mentally. I appreciate her comprehensive approach to wellness, her patience and her ongoing coaching!
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Lisa B
184 days ago
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Michelle is lovely to work with. She takes adequate time to listen and has useful and practical solutions.
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Judith Rosbrook profile picture
Judith Rosbrook
186 days ago
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I’ve been counseling with Michelle for almost a year. She has your best interest at heart! She’s very knowledgeable and recommends what’s best for your health! Thank you for everything Michelle!!! JR
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ilissa siegel
191 days ago
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SpokeMED/Michelle is very knowledgeable and always accessible/helpful. She looks at your health and wellbeing holistically and has helped me feel like the best version of myself.
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Ali Loomis profile picture
Ali Loomis
193 days ago
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Working with Michelle has been wonderful! She is clear, informative, and makes sure all of my questions have been answered. She is personable, supportive, and easy to talk to. I highly recommend her!
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Nancy Hortman
193 days ago
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Michelle, is absolutely wonderful! She is beyond helpful and wise and cares woud recommend !!
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Joni House profile picture
Joni House
199 days ago
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Working with SPOKEmed has truly transformed my health and focus. The guidance, accountability, and encouragement is helping me build better habits and gain clarity. I am thankful for the positive impact they have had on my life.
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Rhina Mendoza
200 days ago
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I have nothing but excellent reviews with this service, very friendly and knowledgeable people, love it , thanks
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Rolanda Montenegro
201 days ago
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Love working with Michelle! She answers all my questions and shows extreme understanding and care with her clients. I felt very good knowing she was there to walk me through this process. Highly recommend her services!
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Katie Norman profile picture
Katie Norman
205 days ago
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Michelle is wonderful! Michelle is so supportive, responsive and encouraging. She truly listens to your concerns and provides sound solutions and guidance. She truly cares for her patients.
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Pawfessional Mobile Vet
210 days ago
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Michelle is wonderful to work with and provides exceptional advice!
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Tim Ellenburg
214 days ago
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Close attention to detail, thorough coverage of information
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L.S.C
220 days ago
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Kas profile picture
Kas
228 days ago
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Michelle is very knowledagble, kind and is always willing to help if I have a question about something. She makes sure she gives enough info on the glp1 shot for her clients to be successful.
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Katie Sefton
234 days ago
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I’ve been working with Michelle for several months and have lost over 50 lbs at a healthy pace. It is easy to arrange appointments and she is flexible with the need to reschedule. She listens well and offers on point advice without judgement. She seems to love helping people on their journey to better health and is very knowledgeable about current best practices. I highly recommend SPOKEmed.
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Jenna
494 days ago
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I can’t say enough positive things about working with Michelle! She has been instrumental in my weight loss journey with GLP-1 and Lipomino injections. She is so supportive, incredibly knowledgeable, and always willing to answer my questions. She truly listens and takes the time to understand my needs and goals. Her availability and accommodating nature have made this process smooth and reassuring. I’m so grateful to have her guidance and expertise!
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Sumner Lane
497 days ago
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Michelle is knowledgeable, attentive, and takes the time to explain her treatments clearly, making me feel comfortable and informed. I appreciate how easy it is to communicate with her and efficiency of visits. She truly cares for her clients and their health.
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Natalie Crain
519 days ago
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Very engaging, cares about my progress, extremely knowledgeable and supportive of my journey.
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Franklin E Corvaia II
542 days ago
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Thank you for your health education and expertise on my weight loss journey.
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Michele Sabin
543 days ago
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I have really enjoyed working with Michelle Middleton. She is helping me reach my optimal health goals with proven solutions, great advice and expertise. She’s incredible!!
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Colleen McKenzie
617 days ago
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I’ve lost 11 lbs in less than 3 weeks. A genuine caring person.
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Melissa Staelens
631 days ago
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Michelle has provided amazing support as I continue in my journey towards better health. She helps provide tools that make getting healthy easier and attainable! So thankful to have found her!
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MM profile picture
MM
634 days ago
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Michelle is just amazing! From our very first conversation she listens to what I am looking for, addresses all my concerns and she patiently answers all my questions. She is also an incredible positive force and a fantastic cheerleader as I continue my journey of growing and learning in regards to my health and happiness!
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Arden Ellis
638 days ago
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Michelle is just the best. She helps you look at the WHOLE picture not just one aspect of your health. It's so important to take the time to really understand each patient's specific needs, issues our health goals, and Michelle does this like no one I've ever met. I am so grateful for her expertise and commitment to her patients.
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Susan Martin
657 days ago
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When one comes across something or someone of exceptional quality, you want to share it. That is what I would like to do w/ Michele Middleton. Michelle reached out to me with a suggestion of treatment and course of action to repair and restore my destructive behavior and thinking the program she believes in is good very good but her skills in repairing and Restoration are exceptional. Never judgmental always viewing it from let’s redirect it. Bottom line always with love the heart of hers is full and giving all the time I find her a gift from above
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Jennifer Riggs
659 days ago
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Michelle- has been there for my health journey every step of the way. She turns a negative into a positive and at times when I wanted to give in, she was right there for me. She is a big part of my success and continues to support me.
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Shannon Perry profile picture
Shannon Perry
660 days ago
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Michelle Middleton, P.A. Is one of the most caring & careful health care professionals I’ve ever encountered! The world needs more Michelle’s!
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Enid Roper
683 days ago
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Michelle is wonderful. Knowledgable, professional, and really explains things well. Made the process so easy.
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Troy M
689 days ago
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Michelle has been absolutely amazing. She is thorough, professional and takes the time to not just listen to my health concerns, but addresses them in a way that is easy to understand. Very pleased with the journey so far and am looking forward to continue my health journey with her. Crystal F.
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Karla McCoy
689 days ago
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Michelle has been an essential part of my health journey. She is knowledgeable, always available to answer my questions when needed, and always ready to help and encourage me. I highly recommend her to anyone ready to start their health journey.
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Marty McCravy
689 days ago
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Michelle is a fantastic coach. She is so knowledgeable and helpful. I highly recommend Michelle for your weight loss journey
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Charlin Burdick
696 days ago
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Michelle is absolutely amazing!!! She is beyond professional and listens to her patients needs and concerns. She has been my guide in this journey answering questions, addressing concerns and helping me bridge the gap in achieving my health & nutrition goals. She is incredibly intelligent & respectful and so easy to connect with as well! Do yourself a favor and schedule a consultation and see for yourself. You’ll thank me later!!
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Gerry Gerrard
736 days ago
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My friend lost 8 pounds in 2 weeks through this program of a healthy lifestyle and healthy eating. She stopped drinking alcohol (which is miraculous) and eats regularly but healthy all day long and feels GREAT! shes in it to win it and can't wait to get to her ideal weight!
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Frequently Asked Questions About
Targeted Peptide Support

Schedule a Consultation with SPOKEmed

A consultation with Michelle Middleton, PA-C, is the first step. She will review your health history, labs, and goals and explain exactly which therapies are appropriate, what to expect, and what the full cost of your plan would be. There is no obligation.

Availability

Monday
8:00 AM - 6:00 PM
Tuesday
8:00 AM - 6:00 PM
Wednesday
8:00 AM - 6:00 PM
Thursday
8:00 AM - 6:00 PM
Friday
8:00 AM - 6:00 PM

All therapies require a clinical consultation prior to prescribing. Investigational therapies carry additional review requirements. Nothing on this page constitutes medical advice.

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