3×4 Genetics
Definition
3×4 Genetics analyzes genetic variants (SNPs — single nucleotide polymorphisms) across metabolic, inflammatory, hormonal, and nutritional pathways rather than focusing on disease risk alone. The 3×4 Genetic Blueprint test examines 36 genes across 12 pathways including methylation (MTHFR and related genes), inflammation, estrogen metabolism, detoxification, cardiometabolic function, hormone production, nutrient metabolism, and stress response. This pathway-level analysis provides clinically actionable insight — not just genetic predisposition scores but specific guidance on nutritional intervention, supplementation needs, and lifestyle optimization tailored to a patient’s genetic profile. Unlike direct-to-consumer genomics, 3×4 reports are designed for clinical interpretation by a trained provider.
Frequently Asked Question
Why 3×4 Genetics Matters
How Spokmed Company Uses It
SPOKEmed uses 3x4 Genetics testing to deepen the precision of clinical protocols — particularly around hormone metabolism (informing HRT decisions), methylation support, inflammatory gene variants, and nutrient metabolism. Genetic results are interpreted in the context of the patient's full clinical picture and used to refine individualized protocols over time.